MIRNA PROFILES IN LYMPHOBLASTOID CELL LINES OF FINNISH PROSTATE CANCER FAMILIES.


CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest

Abstract Background Cell cycle dysregulation is common in human malignancies, and CDK4/6 inhibitors targeting cell cycle have potential antitumor activity.SHR6390 is a novel small molecule inhibitor specifically targeting the CDK4/6 pathway.However, the role of SHR6390 in esophageal squamous cell carcinoma (ESCC) remains unknown, which will be inve

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The ontogenetic osteohistology of Tenontosaurus tilletti.

Tenontosaurus tilletti is an ornithopod dinosaur known from the Early Cretaceous (Aptian-Albian) Cloverly and Antlers formations of the Western United States.It is represented by a large number of specimens spanning a number of ontogenetic stages, and these specimens have been collected across a wide geographic range (from central Montana to southe

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Picturing the Arctic: digital imagery and the prospect of using search engines to collect data for interpretative political research

ABSTRACTImagery frames reality, and political actors tell stories using images.In an increasingly digital communication landscape, political actors tell visual stories directly on websites or social media channels.This online shift places digital imagery centrally in how we picture political issues, events, and places.Digital images are mobile, cir

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